Searching for effective, low cost and less side effect containing herbal hypoglycemic agents is important therefore, the present study was performed to evaluate the effect of olive leaves and stevia leaves of alcoholic extracts on diabetic rats. A total of thirty six male healthy rats, weighing (201±1.5g) were classified in to 2 main groups of extraction of olive leaves and stevia leaves each group was classified into 2 subgroup (levels of each type of extract at 0.2 and 0.5 %); in addition to the control negative (-ve) and the control positive (+ve) groups. The rats were divided into six groups: Group (1), the control negative (-ve) was fed on the basal diet. Group (2), the control positive (+ve) (diabetic rats) was fed on the basal diet. Groups (3 and 4) are diabetic rats fed on the basal diet containing olive leaves extract at 0.2 and 0.5 % respectively. Groups (5 and 6) are diabetic rats groups fed on the basal diet containing stevia leaves extract at 0.2 and 0.5 % respectively.
At the end of the experimental period (6 weeks), rats were sacrificed and blood samples were collected to obtain serum. The results indicated that, STZ treated rats showed significant increase in glucose levels compared to normal rats. Supplementation with different levels of olive leaves and stevia leaves in the diet caused significant decrease (P<0.05) in the concentration of glucose level compared to the positive control one. It was also observed that the concentration of serum lipid profile, liver functions and kidney functions were significantly improved for all tested groups, compared to the positive control group. In conclusions, diet supplemented olive leaves and stevia leaves caused an improvement of the biochemical results from diabetes, therefore olive leaves and stevia leaves could be used as a suitable supplementation therapy for diabetic patients.
S. Abd El-Baky, Mohamed, A. Zaki, Eid, & S. El Haggar, Mayada. (2022). Effect of Some Plant leaves extract on diabetic rats. مجلة دراسات وبحوث التربية النوعية, 8(2), 647-675. doi: 10.21608/jsezu.2022.253039
MLA
Mohamed S. Abd El-Baky; Eid A. Zaki; Mayada S. El Haggar. "Effect of Some Plant leaves extract on diabetic rats", مجلة دراسات وبحوث التربية النوعية, 8, 2, 2022, 647-675. doi: 10.21608/jsezu.2022.253039
HARVARD
S. Abd El-Baky, Mohamed, A. Zaki, Eid, S. El Haggar, Mayada. (2022). 'Effect of Some Plant leaves extract on diabetic rats', مجلة دراسات وبحوث التربية النوعية, 8(2), pp. 647-675. doi: 10.21608/jsezu.2022.253039
VANCOUVER
S. Abd El-Baky, Mohamed, A. Zaki, Eid, S. El Haggar, Mayada. Effect of Some Plant leaves extract on diabetic rats. مجلة دراسات وبحوث التربية النوعية, 2022; 8(2): 647-675. doi: 10.21608/jsezu.2022.253039
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